Which gland is primarily responsible for the secretion of glucagon?

• A. Thyroid gland
• B. Pituitary gland
• C. Pancreas
• D. Adrenal gland

Answer: (C)

The pancreas is primarily responsible for the secretion of glucagon. Glucagon is a hormone produced by the alpha cells of the pancreas, and it plays a crucial role in glucose metabolism in the body. Specifically, glucagon is released when blood glucose levels are low, signaling the liver to convert stored glycogen into glucose and release it into the bloodstream. This process helps to maintain normal blood sugar levels, especially during periods of fasting or intense exercise.

In contrast, the thyroid gland primarily secretes hormones that regulate metabolism, such as thyroxine, and is not involved in glucose regulation. The pituitary gland is often referred to as the "master gland" because it regulates various hormones in the body but does not directly produce glucagon. The adrenal gland is responsible for producing several hormones, including cortisol and adrenaline, which help the body respond to stress but also do not secrete glucagon. Thus, the pancreas is unequivocally the gland that secretes glucagon, making it the correct answer.