Which of the following is a symptom of adrenal insufficiency?

• A. Weight gain
• B. Muscle weakness
• C. Anxiety
• D. Increased appetite

Answer: (B)

Muscle weakness is a prominent symptom of adrenal insufficiency, which occurs when the adrenal glands do not produce enough of the hormones, particularly cortisol. This hormone plays a vital role in energy metabolism, and its deficiency can lead to decreased strength and endurance. Patients may experience fatigue, physical weakness, and unusual tiredness due to the insufficient levels of cortisol required for normal muscle function and energy utilization.

Other symptoms associated with adrenal insufficiency typically include fatigue, loss of appetite, weight loss, low blood pressure, and electrolyte imbalances. While weight gain, anxiety, and increased appetite can be related to various health conditions, they are not characteristic signs of adrenal insufficiency. This understanding highlights muscle weakness as a significant and relevant symptom when diagnosing and managing adrenal insufficiency.